Publications

The molecular and immune landscape of the forkhead-box gene family in different subtypes of breast cancer

Bi X^#, Chen L^#, Wu D^#, Xu D^#, Zheng D, Xu Z, Wan Z, Zheng W^*, Li K^*, Zheng S^*.

Genes & Diseases. 2026.

Integrative Transcriptomic Analysis Decodes the Interplay Between Aging, Senescence, and Cancer

Cai J^#, Wu D^#, Xu D^#, Liu F^#, Li P, Zheng D, Xu Z, Cao M, Shen Y, Zhang N, Tian G, Fan C, Wang B^*, Li K^*, Bi X^*.

Cancer Sci. 2025 Sep 3.

Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer

Guan X^#, Zhang Y^#, Sun R^#, Wang G^#, Bi X^#, Zhang Z, Zan L, Meng Y, Liu Y, Guo J, Ma J, Li J, Hu H, Zhang Y, Zhang X, Liu M, Jiang B, Liu H, Zou S, Xi Y^*, Zhou H^*, Bai W^*, Wu D^*, Wang X^*.

Nat Commun. 2025 Aug 22;16(1):7834.

Impact of lymph node metastasis on immune microenvironment and prognosis in colorectal cancer liver metastasis: insights from multiomics profiling

Zhang Y^#, Wu D^#, Zhang Z^#, Ma J^#, Jiao S, Ma X, Li J, Meng Y, Zhao Z, Chen H, Jiang Z, Wang G, Liu H, Xi Y^*, Zhou H^*, Wang X^*, Guan X^*.

Br J Cancer. 2025 Apr;132(6):513-524.

Activation of hypoxia response in aging cerebral vascular protects male against cognitive impairment

Li P^#, Bi X^#, Xu D^#, Meng Y^#, Xia Y, Cai J, Shen Y, Wang J, Chen J, Wang B^*, Wu D^*, Li K^*.

Aging Cell. 2024 Oct;23(10): e14264.

Single-cell transcriptomic landscape reveals distinct tumourigenesis and immune microenvironments in secondary radiation-exposed rectal cancer

Guan X^#, Bi X^#, Wei R^#, Zhao Z^#, Lu Z, Jiang Z, Wang X^*, Wu D^*.

Clin Transl Med. 2024 Apr;14(4):e1659.

A conserved cell cycle re-entry-senescence evolutionary trajectory in post-mitotic neurons with disease-specific signatures

Wu D, Sun JK, Chow KH*.

Plos Biology. 2024 Apr 23;22(4):e3002559. (Plos Biology editors' top picks for 2024)

Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sex dimorphism in late-onset Alzheimer's disease

Wu D, Bi X, Chow KH*.

Journal of Neuroinflammation. 2024 Jan 4;21(1)

Pan-cancer analyses reveal multi-omic signatures and clinical implementations of the forkhead-box gene family

Bi X^#, Zheng D^#, Cai J^#, Xu D^#, Chen L, Xu Z, Cao M, Li P, Shen Y, Wang H, Zheng W, Wu D^*, Zheng S^*, Li K^*.

Cancer Med. 2023 Aug;12(16):17428-17444.

Enhanced insulin-regulated phagocytic activities support extreme health span and longevity in multiple populations

Wu D^#, Bi X^#, Li P, Xu D, Qiu J, Li K^*, Zheng S^*, Chow KH^*.

Aging Cell. 2023 May;22(5):e13810. (Wiley "Open Science Excellent Author Program")

Chronic alcohol metabolism results in DNA repair infidelity and cell-cycle-induced senescence in neurons

Sun JK^#, Wu D^#, Wong GC, Lau TM, Yang M, Hart RP, Kwan KM, Chan HYE, Chow HM^*.

Aging Cell. 2023 Jan 23;e13772.

NBAS, a gene involved in cytotoxic degranulation, is recurrently mutated in pediatric hemophagocytic lymphohistiocytosis

Bi X^#, Zhang Q^#, Chen L^#, Liu D, Li Y, Zhao X, Zhang Y, Zhang L, Liu J, Wu C, Li Z, Zhao Y, Ma H, Huang G, Liu X^*, Wang QF^*, Zhang R^*.

J Hematol Oncol. 2022 Jul 28;15(1):101. (Highlighted by China Daily and Global Times)

How placenta promotes the successful reproduction in high-altitude populations: a transcriptome comparison between adaptation and acclimatization

Wu D^#, Liu Y^#, Chen W^#, Shao J, Zhuoma P, Zhao D, Yu Y, Liu T, Yu R, Gan Y, Yuzheng B, Huang Y, Zhang H, Bi X, Tao C, Lai S, Luo Q, Zhang D, Wang H, Zhaxi P, Zhang J, Qiao J, Zeng C^*.

Mol Biol Evol. 2022 Jun 2;39(6):msac120.

Selected papers